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Drug discovery

Priming the antimalarial pipeline

Nature volume 465, pages 297–298 (2010)Cite this article

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Emerging resistance to existing antimalarial drugs could nullify efforts to eliminate this deadly disease. The discovery of thousands of agents active against malaria parasites offers hope for developing new drugs.

Malaria affects hundreds of millions of people worldwide, and claims hundreds of thousands of lives every year. These grim statistics could rise even higher should resistance to the existing antimalarial drugs develop further. It is against this backdrop that the papers of Gamo et al.1 and Guiguemde et al.2 merit celebration — in this issue, they describe the identification and chemical structures of vast numbers of compounds, each with the potential to be developed into tomorrow's antimalarial drugs.

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References

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Authors and Affiliations

  1. David A. Fidock is in the Departments of Microbiology and Immunology, and of Medicine (Division of Infectious Diseases), Columbia University Medical Center, New York, New York 10032, USA. df2260@columbia.edu,

    David A. Fidock

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  1. David A. Fidock
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Fidock, D. Priming the antimalarial pipeline. Nature 465, 297–298 (2010). https://doi.org/10.1038/465297a

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