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Gene-expression forum

Decoy for microRNAs

Pseudogenes are considered to be defunct relatives of known genes. But there is some surprising news: pseudogenes are functional and could have a role in the control of cancer1. Two experts discuss the significance of these findings for understanding the regulation of gene expression and cancer biology.

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Figure 1: Evolutionary relatives cooperate.

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Rigoutsos, I., Furnari, F. Decoy for microRNAs. Nature 465, 1016–1017 (2010). https://doi.org/10.1038/4651016a

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