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Gene-expression forum

Decoy for microRNAs

Nature volume 465, pages 1016–1017 (2010)Cite this article

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Pseudogenes are considered to be defunct relatives of known genes. But there is some surprising news: pseudogenes are functional and could have a role in the control of cancer1. Two experts discuss the significance of these findings for understanding the regulation of gene expression and cancer biology.

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Figure 1: Evolutionary relatives cooperate.

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Authors and Affiliations

  1. Isidore Rigoutsos is in the Department of Pathology, Anatomy and Cell Biology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA. isidore.rigoutsos@jefferson.edu,

    Isidore Rigoutsos

  2. Frank Furnari is at the Ludwig Institute for Cancer Research, University of California, San Diego, La Jolla, California 92093, USA. ffurnari@ucsd.edu,

    Frank Furnari

Authors
  1. Isidore Rigoutsos
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  2. Frank Furnari
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Rigoutsos, I., Furnari, F. Decoy for microRNAs. Nature 465, 1016–1017 (2010). https://doi.org/10.1038/4651016a

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