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Materials science

Muscle mimic

An elastic polymer has been made whose molecular structure mimics that of titin, a protein found in muscle. The resulting material is tough, stretchy and dissipates energy — just like muscle itself.

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Figure 1: Unravelling titin.

References

  1. Lv, S. et al. Nature 465, 69–73 (2010).

    ADS  CAS  Article  Google Scholar 

  2. Urry, D. W., Haynes, B., Zhang, H., Harris, R. D. & Prasad, K. U. Proc. Natl Acad. Sci. USA 85, 3407–3411 (1988).

    ADS  CAS  Article  Google Scholar 

  3. Urry, D. W. et al. Phil. Trans. R. Soc. Lond. B 357, 169–184 (2002).

    CAS  Article  Google Scholar 

  4. Cappello, J. et al. Biotechnol. Prog. 6, 198–202 (1990).

    CAS  Article  Google Scholar 

  5. Rabotyagova, O. S., Cebe, P. & Kaplan, D. L. Biomacromolecules 10, 229–236 (2009).

    CAS  Article  Google Scholar 

  6. Elvin, C. M. et al. Nature 437, 999–1002 (2005).

    ADS  CAS  Article  Google Scholar 

  7. Kim, W. & Conticello, V. P. J. Macromol. Sci. C 47, 93–119 (2007).

    CAS  Google Scholar 

  8. Cao, Y. & Li, H. Nature Mater. 6, 109–114 (2007).

    ADS  CAS  Article  Google Scholar 

Download references

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Competing interests

Elliot L. Chaikof has submitted intellectual property in the area of elastomeric proteins and is a scientific founder of Ontogenesys, Inc., which seeks to utilize these materials in clinical applications.

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Chaikof, E. Muscle mimic. Nature 465, 44–45 (2010). https://doi.org/10.1038/465044a

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