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Host and microbes in a pickle

An Addendum to this article was published on 05 May 2010

Metabolic disorders such as obesity are characterized by long-term, low-grade inflammation. Under certain conditions, the resident microorganisms of the gut might contribute to this inflammation, resulting in disease.

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Figure 1: Host–microbe communication in systemic inflammation.


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Gökhan Hotamisligil is on the scientific advisory board, is a shareholder and receives research support from Syndexa Pharmaceuticals.

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Li, P., Hotamisligil, G. Host and microbes in a pickle. Nature 464, 1287–1288 (2010).

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