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DNA repair

A heavyweight joins the fray

Tagging of DNA-damage-associated proteins by ubiquitin is key to coordinating the DNA-damage response. The ubiquitin-related protein SUMO is revealed as a crucial regulator of ubiquitylation in DNA repair.

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Figure 1: Ubiquitylation and SUMOylation at DSBs.


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Boulton, S. A heavyweight joins the fray. Nature 462, 857–858 (2009).

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