The ring-shaped helicase enzyme Rho moves along RNA using ATP as an energy source. Coordinating ATP hydrolysis with nucleic-acid binding seems to determine the direction and mechanism of helicase movement.
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References
Patel, S. S. & Picha, K. M. Annu. Rev. Biochem. 69, 651–697 (2000).
Thomsen, N. D. & Berger, J. M. Cell 139, 523–534 (2009).
Schwartz, A. et al. Nature Struct. Mol. Biol. doi:10.1038/nsmb.1711 (2009).
Skordalakes, E. & Berger, J. M. Cell 114, 135–146 (2003).
Wei, R. R. & Richardson, J. P. J. Biol. Chem. 276, 28380–28387 (2001).
Enemark, E. J. & Joshua-Tor, L. Nature 442, 270–275 (2006).
Boyer, P. D. Annu. Rev. Biochem. 66, 717–749 (1997).
Moffitt, J. R. et al. Nature 457, 446–450 (2009).
Donmez, I. & Patel, S. S. EMBO J. 27, 1718–1726 (2008).
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Patel, S. Steps in the right direction. Nature 462, 581–583 (2009). https://doi.org/10.1038/462581a
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DOI: https://doi.org/10.1038/462581a
