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Structural biology

New beginnings for transcription

A structure for the enzyme RNA polymerase II in combination with the transcription factor TFIIB changes our view of how the polymerase and its helper proteins initiate transcription.

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Figure 1: Structures of RNA polymerase II in combination with the general transcription factor TFIIB.

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Hahn, S. New beginnings for transcription. Nature 462, 292–293 (2009). https://doi.org/10.1038/462292a

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