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Drug discovery

Propping up a destructive regime

The Wnt signalling pathway balances the opposing activities of two proteins to transmit signals within cells. An inhibitor that stabilizes one of these proteins reveals a new target for anticancer drug development.

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Figure 1: The Wnt-signalling seesaw.

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Peterson, R. Propping up a destructive regime. Nature 461, 599–600 (2009). https://doi.org/10.1038/461599a

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