Aquatic Toxicol. doi:10.1016/j.aquatox.2009.08.001 (2009)

Pollutants such as effluent wastewater, pesticides and pharmaceuticals in rivers are suspected to cause the intersex condition in fish, in which reproductive tissues are mismatched: most often, female germ cells are present in the testes.

To assess the incidence of the condition in river fish throughout the United States, Jo Ellen Hinck, a US Geological Survey scientist in Columbia, Missouri, and her team sampled 111 sites spread across the country. Intersex fish were found in 31% of the sites, with the greatest prevalence in the south-east. Small and largemouth bass were the species most commonly affected.