It seems that growth factors may instruct blood-cell progenitors to develop into specific mature cell types, actively determining lineage choice. But is this reductionist view of cell fate overly simplistic?
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Enver, T., Jacobsen, S. Instructions writ in blood. Nature 461, 183–184 (2009). https://doi.org/10.1038/461183a
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DOI: https://doi.org/10.1038/461183a