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Developmental biology

A cellular view of regeneration

How the salamander regrows an entire limb after injury has flummoxed the wisest of scientists. A closer look at the cells involved in limb regeneration shows that remembering past origins may be crucial for this feat.

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Figure 1: Cell-tracking techniques used by Kragl and colleagues1.
Figure 2: Lineages are respected during axolotl limb regeneration.

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Sánchez Alvarado, A. A cellular view of regeneration. Nature 460, 39–40 (2009). https://doi.org/10.1038/460039a

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