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Cell biology

The proteasome assembly line

The assembly of the proteasome — the cellular machine that eliminates unwanted proteins — is a carefully choreographed affair, involving a complex sequence of steps overseen by dedicated protein chaperones.

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Figure 1: A model of proteasome regulatory-particle assembly1,2.


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Madura, K. The proteasome assembly line. Nature 459, 787–788 (2009).

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