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Systems biology

When it is time to die

Why do cells of the same population respond differently to external death-inducing stimuli? Individuality seems to originate from non-genetic differences in the levels and activation states of proteins.

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Figure 1: Non-genetic factors contribute to the rate of apoptosis.


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Bastiaens, P. When it is time to die. Nature 459, 334–335 (2009).

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