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Cell biology

A score for membrane fusion

Intracellular membrane fusion has been mimicked in vitro using a mix of 17 purified proteins and lipid bilayers. This technical tour de force allows the study of how cells orchestrate and perform such fusion events.

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Figure 1: Proteins work together to mediate endosomal membrane fusion.

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Collins, R., Zimmerberg, J. A score for membrane fusion. Nature 459, 1065–1066 (2009). https://doi.org/10.1038/4591065a

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