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Biochemistry

Anchors away

Nature often adopts several approaches to crack the same problem. The finding that the mechanism of a crucial enzyme in certain disease-causing bacteria differs from that in mammals offers scope for drug discovery.

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Figure 1: Different mechanisms in the biosynthesis of dTMP.

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Costi, M., Ferrari, S. Anchors away. Nature 458, 840–841 (2009). https://doi.org/10.1038/458840a

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