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Immunology

Cause of death matters

The process of programmed cell death can either induce anti-inflammatory immune responses or actively promote inflammation. Whether the dying cell is infected seems to govern which response is triggered.

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Figure 1: Infection, apoptosis and immune responses.

References

  1. Torchinsky, M. B., Garaude, J., Martin, A. P. & Blander, J. M. Nature 458, 78–82 (2009).

    ADS  CAS  Article  Google Scholar 

  2. Veldhoen, M. et al. Immunity 24, 179–189 (2006).

    CAS  Article  Google Scholar 

  3. Veldhoen, M., Hockin g, R. J., Flavell, R. A. & Stockinger, B. Nature Immunol. 7, 1151–1156 (2006).

    CAS  Article  Google Scholar 

  4. Li, M. O., Wan, Y. Y. & Flavell, R. A. Immunity 26, 579–591 (2007).

    CAS  Article  Google Scholar 

  5. Chen, W., Frank, M. E., Jin, W. & Wahl, S. M. Immunity 14, 715–725 (2001).

    CAS  Article  Google Scholar 

  6. Fadok, V. A. et al. J. Clin. Invest. 101, 890–898 (1998).

    CAS  Article  Google Scholar 

  7. Voll, R. E. et al. Nature 390, 350–351 (1997).

    ADS  CAS  Article  Google Scholar 

  8. Bettelli, E. et al. Nature 441, 235–238 (2006).

    ADS  CAS  Article  Google Scholar 

  9. Mangan, P. R. et al. Nature 441, 231–234 (2006).

    ADS  CAS  Article  Google Scholar 

  10. Liston, A. & Rudensky, A. Y. Curr. Opin. Immunol. 19, 176–185 (2007).

    CAS  Article  Google Scholar 

  11. LeibundGut-Landmann, S. et al. Nature Immunol. 8, 630–638 (2007).

    CAS  Article  Google Scholar 

Download references

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Stockinger, B. Cause of death matters. Nature 458, 44–45 (2009). https://doi.org/10.1038/458044a

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