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Developmental biology

Birth of the blood cell

Could it be that mouse fetal liver cells and adult bone-marrow blood cells originate from a subset of cells that line the blood vessels in the embryo? Several lines of evidence suggest that this is indeed the case.

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Figure 1: Relationship between endothelial cells and blood cells.

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Yoshimoto, M., Yoder, M. Birth of the blood cell. Nature 457, 801–803 (2009). https://doi.org/10.1038/457801a

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