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Evolutionary genomics

A positive becomes a negative

Which human genes have been hotspots for positive selection? Analyses of the top candidates reveal, not genes subject to such selection, but genes that have probably been subject to biased DNA repair.

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Figure 1: Identification of a gene segment showing unusually rapid evolution.


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Hurst, L. A positive becomes a negative. Nature 457, 543–544 (2009).

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