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Immunology

Barrier to electrical storms

Nature volume 457, pages 155–156 (2009)Cite this article

Epilepsy is characterized by repetitive seizures due to abnormal electrical activity in the brain. Immune cells promote development of this disorder by mediating the breakdown of the blood–brain barrier.

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Figure 1: Role of the immune system in epilepsy.

References

  1. Janigro, D. Epilepsy Curr. 7, 105–107 (2007).

    Article  Google Scholar 

  2. Kim, J. V., Kang, S. S., Dustin, M. L. & McGavern, D. B. Nature 457, 191–195 (2009).

    Article  ADS  CAS  Google Scholar 

  3. Fabene, P. F. et al. Nature Med. 14, 1377–1383 (2008).

    Article  CAS  Google Scholar 

  4. Kivisakk, P. et al. Ann. Neurol. doi:10.1002/ana.21379 (2008).

  5. Ransohoff, R. M., Kivisakk, P. & Kidd, G. Nature Rev. Immunol. 3, 569–581 (2003).

    Article  CAS  Google Scholar 

  6. Marchi, N. et al. Epilepsia 48, 732–742 (2007).

    Article  CAS  Google Scholar 

  7. van Vliet, E. A. et al. Brain 130, 521–534 (2007).

    Article  CAS  Google Scholar 

  8. Ivens, S. et al. Brain 130, 535–547 (2007).

    Article  Google Scholar 

  9. Rigau, V. et al. Brain 130, 1942–1956 (2007).

    Article  Google Scholar 

  10. Ransohoff, R. M. N. Engl. J. Med. 356, 2622–2629 (2007).

    Article  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Department of Neurosciences, Richard M. Ransohoff is at the Neuroinflammation Research Center, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA. ransohr@ccf.org,

    Richard M. Ransohoff

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  1. Richard M. Ransohoff
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Ransohoff, R. Barrier to electrical storms. Nature 457, 155–156 (2009). https://doi.org/10.1038/457155a

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