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Epigenetics

How to lose a tail

Everyone carries some baggage they would like to lose. For the histone protein H3, that baggage is a chunk of its tail, which when clipped off affects the expression of genes with which the histone is associated.

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Figure 1: Cleavage of the H3 amino-terminal tail.

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Osley, M. How to lose a tail. Nature 456, 885–886 (2008). https://doi.org/10.1038/456885a

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