Some alcohols can't be made in a way that controls the crucial arrangement of chemical groups in the molecule. A reaction that uses common laboratory reagents offers a practical route to these compounds.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Eliel, E. L. & Wilen, S. H. Stereochemistry of Organic Compounds (Wiley, 1994).
Walsh, P. J. & Kozlowski, M. C. Fundamentals of Asymmetric Catalysis (Univ. Sci. Books, 2008).
Biocatalysis (Nature Insight) Nature 409, 225–268 (2001).
Cox, G. B. (ed.) Preparative Enantioselective Chromatography (Blackwell, 2005).
Jacques, J., Collet, A. & Wilen, S. H. Enantiomers, Racemates and Resolutions (Wiley, 1981).
Stymiest, J. L., Bagutski, V., French, R. M. & Aggarwal, V. K. Nature 456, 778–782 (2008).
Leitereg, T. J., Guadangi, D. G., Harris, J., Mon, T. R. & Teranishi, R. J. Agric. Food Chem. 19, 785–787 (1971).
Rouhi, M. Chem. Eng. News 83 (25), 122–123 (2005).
Riant, O. & Hannedouche, J. Org. Biomol. Chem. 5, 873–888 (2007).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Hansen, K. How to beat an alcohol problem. Nature 456, 711–712 (2008). https://doi.org/10.1038/456711a
Published:
Issue Date:
DOI: https://doi.org/10.1038/456711a
This article is cited by
-
Chemo-enzymatic asymmetric synthesis of S-citalopram by lipase-catalyzed cyclic resolution and stereoinversion of quaternary stereogenic center
Bioprocess and Biosystems Engineering (2013)