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Ion channels

The voltage-sensor quartet

Nature volume 456, pages 183–185 (2008)Cite this article

Decoding the workings of voltage-gated sodium channels is crucial because their mutation leads to severe disease and their activity is modulated by toxins and drugs. An innovative approach now allows such investigations.

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Figure 1: Chimaera channels.

References

  1. Bosmans, F., Martin-Eauclaire, M.-F. & Swartz, K. Nature 456, 202–208 (2008).

    Article  ADS  CAS  Google Scholar 

  2. Yellen, G. Q. Rev. Biophys. 31, 239–295 (1998).

    Article  CAS  Google Scholar 

  3. Jiang, Y. et al. Nature 423, 33–41 (2003).

    Article  ADS  CAS  Google Scholar 

  4. Jiang, Y. et al. Nature 423, 42–48 (2003).

    Article  ADS  CAS  Google Scholar 

  5. Chanda, B., Asamoah, O. K. & Bezanilla, F. J. Gen. Physiol. 123, 217–230 (2004).

    Article  CAS  Google Scholar 

  6. Jiang, Y. et al. Nature 432, 33–41 (2003).

    Article  ADS  Google Scholar 

Download references

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Authors and Affiliations

  1. J. R. Bankston and R. S. Kass are in the Department of Pharmacology, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA. rsk20@columbia.edu,

    J. R. Bankston & R. S. Kass

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  1. J. R. Bankston
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  2. R. S. Kass
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Bankston, J., Kass, R. The voltage-sensor quartet. Nature 456, 183–185 (2008). https://doi.org/10.1038/456183a

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