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Ion channels

The voltage-sensor quartet

Decoding the workings of voltage-gated sodium channels is crucial because their mutation leads to severe disease and their activity is modulated by toxins and drugs. An innovative approach now allows such investigations.

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Figure 1: Chimaera channels.

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Bankston, J., Kass, R. The voltage-sensor quartet. Nature 456, 183–185 (2008). https://doi.org/10.1038/456183a

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