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Helpful T cells are sticky

Prolonged physical interaction between helper T cells and antibody-producing B cells is crucial for efficient immune responses. Mutations in a protein that underlies this process cause human disease.

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Figure 1: Role of SAP in immune responses mediated by T and B cells.


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Deenick, E., Tangye, S. Helpful T cells are sticky. Nature 455, 745–747 (2008).

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