To make one differentiated cell type from another, a 'stopover' at an undifferentiated state is often required. An alternative method offering an efficient direct route could have implications for disease treatment.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Murry, C. E. & Keller, G. Cell 132, 661–680 (2008).
Zhou, Q., Brown, J., Kanarek, A., Rajagopal, J. & Melton, D. A . Nature 455, 627–632 (2008).
Hochedlinger, K. & Jaenisch, R. Nature 441, 1061–1067 (2006).
Takahashi, K. & Yamanaka, S. Cell 126, 663–676 (2006).
Park, I.-H. et al. Cell 134, 877–886 (2008).
Dimos, J. T. et al. Science 321, 1218–1221 (2008).
Rodic´, N., Rutenberg, M. S. & Terada, N. Trends Mol. Med. 10, 93–96 (2004).
Meivar-Levy, I. & Ferber, S. Trends Endocrinol. Metab. 14, 460–466 (2003).
Ber, I. et al. J. Biol. Chem. 278, 31950–31957 (2003).
Kojima, H. et al. Nature Med. 9, 596–603 (2003).
Oliver-Krasinski, J. M. & Stoffers, D. A. Genes Dev. 22, 1998–2021 (2008).
Hasbrouck, N. C. & High, K. A. Gene Therapy 15, 870–875 (2008).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Blelloch, R. Short cut to cell replacement. Nature 455, 604–605 (2008). https://doi.org/10.1038/455604a
Published:
Issue Date:
DOI: https://doi.org/10.1038/455604a
