Abstract
The industrial importance of molecular materials chemistry has promoted great interest in areas such as self-assembled surface coatings1, multi-layer formation on solid substrates2, crystallization from solutions3, crystal morphology4 and structure prediction5, solving structures from powders6 and control of polymorphism7. Improvements in our understanding of the role of intermolecular interactions in driving molecular self-assembly and interfacial processes have led to technological advances—both in controlling the assembly of molecules at the nanometre scale, and in manipulating processes and products in which crystal nucleation and growth are key elements8. But there has been relatively little work on molecular-scale engineering at solid–solid interfaces, despite their importance in polymeric composites for structured and electronic applications, in adhesives and in formulated pharmaceutical and agrochemical products. Here we report the use of molecules as tailored adhesives—a molecular ‘glue’ is selected to bond across an interfacial region and hence stabilize a solid–solid interface. We consider a simple interface occurring in a twinned crystal of saccharin; additive molecules with predictable dimensions and hydrogen-bonding functionality can span the interface. The stabilization is reflected in an enhanced frequency of twin-crystal formation.
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References
Maoz,R., Matlis,S., Dimasi,E., Ocko,B. M. & Sagiv,J. Self-replicating amphiphilic monolayers. Nature 384, 150–153 (1996).
Hatzor,A. et al. Coordination-controlled self-assembled multilayers on gold. J. Am. Chem. Soc. 120, 13469–13477 (1998).
Weissbuch,I., Popvitz-Biro,R., Leiserowitz,L. & Lahav,M. in The Lock and Key Principle (ed. Behr, J. P.) 173–246 (Wiley & Sons, Chichester, 1994).
Docherty,R. & Roberts,K. J. Modelling the morphology of molecular crystals. J. Cryst. Growth 88, 159–168 (1988).
Gavazotti,A. & Fillipini,G. Polymorphic forms of organic crystals at room conditions: thermodynamic and structural implications. J. Am. Chem. Soc. 117, 12299–12305 (1995).
Docherty,R. & Jones,W. in Organic Molecular Solids—Properties and Applications (ed. Jones, W.) Ch. 5 (CRC Press, London, 1997).
Davey,R. J., Blagden,N., Potts,G. D. & Docherty,R. Polymorphism in molecular crystals: stabilization of a metastable form by conformational mimicry. J. Am. Chem. Soc. 119, 1767–1772 (1997).
Davey,R. J., Maginn,S. J. & Polywka,L. in Advances in Industrial Crystallisation 150–165 (Butterworth-Heineman, Oxford, 1991).
Lieberman,H. F., Williams,L., Davey,R. J. & Pritchard,R. G. Molecular configuration at the solid-solid interface: twinning in saccharin crystals. J. Am. Chem. Soc. 120, 686–691 (1998).
Williams-Seton,L., Davey,R. J. & Liebermann,H. F. Solution chemistry and twinning in saccharin crystals: a combined probe for the structure and functionality of the crystal-fluid interface. J. Am. Chem. Soc. 121, 4563–4567 (1999).
Cerius2 version 2.0 (Molecular Simulations Inc., Cambridge, UK, 1998).
Gidalevitz,D. et al. Angew. Chem. Int. Edn Engl. 36, 955–959 (1997).
Acknowledgements
L.W.-S. and H.F.L. acknowledge support from ROPA awards.
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Davey, R., Williams-Seton, L., Lieberman, H. et al. Stabilizing a solid–solid interface with a molecular-scale adhesive. Nature 402, 797–799 (1999). https://doi.org/10.1038/45527
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DOI: https://doi.org/10.1038/45527
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