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Neuroscience: Standard model

Questions raised about the use of 'ALS mice' are prompting a broad reappraisal of the way that drugs are tested in animal models of neurodegenerative disease. Jim Schnabel reports.

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Additional information

Jim Schnabel is a freelance writer based in Maryland.

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Focus on Neurodegeneration

User’s Guide to the Mouse

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ALS Therapy Development Institute

National Institute of Neurological Disorders and Stroke

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Schnabel, J. Neuroscience: Standard model. Nature 454, 682–685 (2008).

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