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Thoroughly modern meiosis

Meiotic recombination shuffles the genome, so each generation inherits a new combination of parental traits. Combining traditional and modern approaches, new work pinpoints where recombination occurs genome-wide.

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Figure 1: Detecting meiotic recombination.


  1. Mancera, E., Bourgon, R., Brozzi, B., Huber, W. & Steinmetz, L. M. Nature 454, 479–485 (2008).

    CAS  Article  ADS  Google Scholar 

  2. Fogel, S., Mortimer, R., Lusnak, K. & Tavares, F. Cold Spring Harb. Symp. Quant. Biol. 43, 1325–1341 (1979).

    CAS  Article  Google Scholar 

  3. Wei, W. et al. Proc. Natl Acad. Sci. USA 104, 12825–12830 (2007).

    CAS  Article  ADS  Google Scholar 

  4. Pan, J. & Keeney, S. PLoS Biol. 5, e333 (2007).

    Article  Google Scholar 

  5. Bishop, D. K. & Zickler, D. Cell 117, 9–15 (2004).

    CAS  Article  Google Scholar 

  6. Mortimer, R. K. & Fogel, S. in Mechanisms in Recombination (ed. Grell, R. F.) 263–275 (Plenum, 1974).

    Book  Google Scholar 

  7. Malkova, A. et al. Genetics 168, 49–63 (2004).

    CAS  Article  Google Scholar 

  8. Borts, R. H. & Haber, J. E. Science 237, 1459–1465 (1987).

    CAS  Article  ADS  Google Scholar 

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Lichten, M. Thoroughly modern meiosis. Nature 454, 421–422 (2008).

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