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Physiology

Myoglobin's new clothes

Nitric oxide generated from the nitrite ion limits the tissue damage caused by restricted blood flow. Gene knockout experiments in mice now reveal that myoglobin is the mediator of this effect.

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Figure 1: Myoglobin as a reductase and an oxygenase.

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Cossins, A., Berenbrink, M. Myoglobin's new clothes. Nature 454, 416–417 (2008). https://doi.org/10.1038/454416a

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