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Structural biology

Snapshots of DNA repair

In recombinational DNA repair, nearly identical sequences in chromosomes are found and swapped. Structures of the RecA–DNA complexes involved provide insight into the mechanism and energetics of this universal process.

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Figure 1: DNA strand exchange promoted by RecA protein.

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Kowalczykowski, S. Snapshots of DNA repair. Nature 453, 463–465 (2008). https://doi.org/10.1038/453463a

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