Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Biophysics

Cells get in shape for a crawl

A cell's shape changes as it moves along a surface. The forward-thinking cytoskeletal elements are all for progress, but the conservative cell membrane keeps them under control by physically opposing their movement.

This is a preview of subscription content, access via your institution

Access options

Buy article

Get time limited or full article access on ReadCube.

$32.00

All prices are NET prices.

Figure 1: Shape matters.

References

  1. Lauffenburger, D. A. & Horwitz, A. F. Cell 84, 359–369 (1996).

    CAS  Article  Google Scholar 

  2. Ridley, A. J. et al. Science 302, 1704–1709 (2003).

    ADS  CAS  Article  Google Scholar 

  3. Keren, K. et al. Nature 453, 475–480 (2008).

    ADS  CAS  Article  Google Scholar 

  4. Pollard, T. D., Blanchoin, L. & Mullins, R. D. Annu. Rev. Biophys. Biomol. Struct. 29, 545–576 (2000).

    CAS  Article  Google Scholar 

  5. Pollard, T. D. & Borisy, G. G. Cell 112, 453–465 (2003).

    CAS  Article  Google Scholar 

  6. Lacayo, C. I. et al. PLoS Biol. 5, e233 (2007).

    Article  Google Scholar 

  7. Mogilner, A. Curr. Opin. Cell Biol. 18, 32–39 (2006).

    CAS  Article  Google Scholar 

  8. Mogilner, A., Wollman, R. & Marshall, W. F. Dev. Cell 11, 279–287 (2006).

    CAS  Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Haugh, J. Cells get in shape for a crawl. Nature 453, 461–462 (2008). https://doi.org/10.1038/453461a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/453461a

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing