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Signal transduction

The rhodopsin story continued

Determination of the architecture of an invertebrate photoreceptor protein, squid rhodopsin, is a notable event. It illuminates the mechanism of invertebrate vision and a ubiquitous intracellular signalling system.

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Figure 1: The architecture of squid rhodopsin, as determined by Murakami and Kouyama2.

References

  1. Hardie, R. C. & Postma, M. in The Senses: A Comprehensive Reference Vol. 1 (ed. Basbaum, A. I.) 77–130 (Academic, San Diego, 2008).

    Book  Google Scholar 

  2. Murakami, M. & Kouyama, T. Nature 453, 363–367 (2008).

    Article  ADS  CAS  Google Scholar 

  3. Hardie, R. C. & Raghu, P. Nature 413, 186–193 (2001).

    Article  ADS  CAS  Google Scholar 

  4. Davies, A. et al. J. Mol. Biol. 314, 455–463 (2001).

    Article  CAS  Google Scholar 

  5. Murakami, M., Kitahara, R., Gotoh, T. & Kouyama, T. Acta Crystallogr. F 63, 475–479 (2007).

    Article  CAS  Google Scholar 

  6. Kobilka, B. & Schertler, G. F. Trends Pharmacol. Sci. 29, 79–83 (2008).

    Article  CAS  Google Scholar 

  7. Li, J. et al. J. Mol. Biol. 343, 1409–1438 (2004).

    Article  CAS  Google Scholar 

  8. Melyan, Z., Tarttelin, E. E., Bellingham, J., Lucas, R. J. & Hankins, M. W. Nature 433, 741–745 (2005).

    Article  ADS  CAS  Google Scholar 

  9. Hankins, M. W., Peirson, S. N. & Foster, R. G. Trends Neurosci. 31, 27–36 (2008).

    Article  CAS  Google Scholar 

Download references

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Gebhard F. X. Schertler is a shareholder of, and scientific adviser to, Heptares Therapeutics, 1-3 Burtonhole Lane, Mill Hill, London NW7 1AD, UK (http://home2.btconnect.com/heptares/). This company is involved in research on G-protein-coupled receptors and drug design.

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Schertler, G. The rhodopsin story continued. Nature 453, 292–293 (2008). https://doi.org/10.1038/453292a

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