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Cell biology


A protein called small ubiquitin-related modifier (SUMO) can be coupled to other proteins to control their function. This SUMOylation has been implicated in the regulation of a host of cellular processes, and is essential for the health, and even the survival, of most organisms.

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Figure 1: SUMO conjugation and deconjugation.
Figure 2: SUMOylation and localization of target proteins.


Figure 3: Molecular switches.
Figure 4: SUMOylation is influenced by and affects a plethora of pathways.

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Meulmeester, E., Melchior, F. SUMO. Nature 452, 709–711 (2008).

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