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Circadian rhythms

Stem cells traffic in time

Circadian activity in the brain regulates the movement of blood stem cells into and out of the bone marrow. Perhaps this process is testing the suitability of these cell 'tenants' for their new home — the remodelling bone.

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Figure 1: Pacemaker activity and cooperativity between bone and bone-marrow cells.


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Scadden, D. Stem cells traffic in time. Nature 452, 416–417 (2008).

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