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Ion channels

Coughing up flu's proton channels

Two research teams have captured snapshots of the influenza virus's membrane-bound hydrogen-ion channel, which is essential for infection and virulence. Their findings agree on the basics, but differ in details.

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Figure 1: Depictions of the M2 proton channel.

References

  1. Stouffer, A. L. et al. Nature 451, 596–599 (2008).

    Article  ADS  CAS  Google Scholar 

  2. Schnell, J. R. & Chou, J. J. Nature 451, 591–595 (2008).

    Article  ADS  CAS  Google Scholar 

  3. Helenius, A. Cell 69, 577–578 (1992).

    Article  CAS  Google Scholar 

  4. Pinto, L. H. & Lamb, R. A. J. Biol. Chem. 281, 8997–9000 (2006).

    Article  CAS  Google Scholar 

  5. Sakaguchi, T., Tu, Q., Pinto, L. H. & Lamb, R. A. Proc. Natl Acad. Sci. USA 94, 5000–5016 (1997).

    Article  ADS  CAS  Google Scholar 

  6. Bright, R. A. et al. Lancet 366, 1175–1181 (2005).

    Article  CAS  Google Scholar 

  7. Wang, C., Takeuchi, K., Pinto, L. H. & Lamb, R. A. J. Virol. 67, 5585–5594 (1993).

    CAS  PubMed  PubMed Central  Google Scholar 

  8. Czabotar, P. E., Martin, S. R. & Hay, A. J. Virus Res. 99, 57–61 (2004).

    Article  CAS  Google Scholar 

  9. Salom, D., Hill, B. R., Lear, J. D. & DeGrado, W. F. Biochemistry 39, 14160–14170 (2000).

    Article  CAS  Google Scholar 

  10. Hu, J. et al. Proc. Natl Acad. Sci. USA 103, 6865–6870 (2006).

    Article  ADS  CAS  Google Scholar 

Download references

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Miller, C. Coughing up flu's proton channels. Nature 451, 532–533 (2008). https://doi.org/10.1038/451532a

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