Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Virology: The battle within

Nature volume 451, pages 388–389 (2008)Cite this article

Viral and microbial interactions within living tissues are more complex than previously thought. Melinda Wenner explores whether a periodic table of the infectious could help sort out the mess.

In 2001, Paolo Lusso asked his colleague Leonid Margolis for a favour. Lusso, a virologist at the San Raffaele Scientific Institute in Milan, Italy, had recently discovered that HIV patients are often co-infected with human herpesvirus 6 (HHV-6). Although typically benign, HHV-6 seemed to hasten HIV progression, and no one knew why. Lusso was studying HHV-6's effects on lymphoid cells but wanted to see what the virus did to whole pieces of lymphoid tissue. So he asked Margolis, a virologist at the US National Institute of Child Health and Human Development in Bethesda, Maryland, and an expert on three-dimensional-tissue, to perform some experiments for him.

This is a preview of subscription content, access via your institution

Access options

Rent or buy this article

Prices vary by article type

from$1.95

to$39.95

Learn more

Prices may be subject to local taxes which are calculated during checkout

References

  1. Grivel, J. C. et al. Nature Med. 7, 1232?1235 (2001).

    Article  Google Scholar 

  2. Barton, E. S. et al. Nature 447, 326?329 (2007).

    Article  Google Scholar 

  3. Best, S., Le Tissierb, P. R. & Stoyeb, J. P. Trends Microbiol. 5, 313?318 (1997).

    Article  Google Scholar 

  4. Lisco, A. et al. J. Virol. 81, 708?717 (2007).

    Article  Google Scholar 

  5. Xiang, J. et al. N. Engl. J. Med. 345, 707?714 (2001).

    Article  Google Scholar 

  6. Kish-Catalone, T. et al. AIDS Res. Hum. Retrovir. 23, 33?42 (2007).

    Article  Google Scholar 

Download references

Authors
  1. Melinda Wenner
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Melinda Wenner is a science writer based in New York City.

Related links

Related links

Related links in Nature Research

Nature Insight: Host-Pathogen interactions

Web Focus on Plant-Microbe interactions

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Wenner, M. Virology: The battle within. Nature 451, 388–389 (2008). https://doi.org/10.1038/451388a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/451388a

This article is cited by

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing