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Immunology

Cascade into clarity

Nature volume 451, pages 254–255 (2008)Cite this article

Immune mediator molecules such as antimicrobial peptides are crucial for host responses to pathogens. Akirins are the latest identified components of a signalling cascade that leads to these responses in insects and mice.

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Figure 1: Role of Akirin proteins in producing immune mediators following microbial infection.

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Authors and Affiliations

  1. Fayyaz S. Sutterwala is in the Department of Medicine, Inflammation Program, University of Iowa, Iowa City, Iowa 52241, USA. fayyaz-sutterwala@uiowa.edu,

    Fayyaz S. Sutterwala

  2. Richard A. Flavell is in the Department of Immunobiology and the Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, Connecticut 06520, USA. richard.flavell@yale.edu,

    Richard A. Flavell

Authors
  1. Fayyaz S. Sutterwala
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  2. Richard A. Flavell
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Sutterwala, F., Flavell, R. Cascade into clarity. Nature 451, 254–255 (2008). https://doi.org/10.1038/451254a

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