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Epigenetics

Reversing the 'irreversible'

“Do not speak — unless it improves on silence” is generally wise advice, and is even vital for a subset of essential genes. New studies describe how, when appropriate, the silence of these genes is broken.

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Figure 1: Reversal of Polycomb-group silencing by demethylases.

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Jones, R. Reversing the 'irreversible'. Nature 450, 357–359 (2007). https://doi.org/10.1038/450357a

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