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  • Original Article
  • Published:

Factors influencing pain during transrectal ultrasonography-guided prostate biopsy

  • K S Han1 &
  • K H Lee1 on behalf of
  • The Korean Urologic Oncology Society Prostate Cancer Study Group

Prostate Cancer and Prostatic Diseases volume 11, pages 139–142 (2008)Cite this article

Abstract

We prospectively investigated the clinical parameters that influenced pain during prostate biopsies. From 12 hospitals 1781 patients were enrolled. The patients completed a visual analogue scale questionnaire for the pain during the procedure. Age, enema preparation, analgesia use and number of biopsy punctures influenced the level of pain during prostate biopsy in univariate linear regression analysis. However, multivariate analysis showed enema preparation, analgesia use and number of biopsy punctures were independent factors associated with the pain during the procedure. Our study confirmed enema preparation before biopsy and the number of biopsy punctures were associated with the pain during prostate biopsy.

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References

  1. Philip J, McCabe JE, Roy SD, Samsudin A, Campbell IM, Javle P . Site of local anaesthesia in transrectal ultrasonography-guided 12-core prostate biopsy: does it make a difference? BJU Int 2006; 97: 263–265.

    Article  PubMed  Google Scholar 

  2. Hsing AW, Tsao L, Devesa SS . International trends and patterns of prostate cancer incidence and mortality. Int J Cancer 2000; 85: 60–67.

    Article  CAS  PubMed  Google Scholar 

  3. De Sio M, D'Armiento M, Di Lorenzo G, Damiano R, Perdona S, De Placido S et al. The need to reduce patient discomfort during transrectal ultrasonography-guided prostate biopsy: what do we know? BJU Int 2005; 96: 977–983.

    Article  PubMed  Google Scholar 

  4. Leibovici D, Zisman A, Siegel YI, Sella A, Kleinmann J, Lindner A . Local anesthesia for prostate biopsy by periprostatic lidocaine injection: a double-blind placebo controlled study. J Urol 2002; 167: 563–565.

    Article  PubMed  Google Scholar 

  5. Djavan B, Zlotta A, Remzi M, Ghawidel K, Basharkhah A, Schulman CC et al. Optimal predictors of prostate cancer on repeat prostate biopsy: a prospective study of 1051 men. J Urol 2000; 163: 1144–1148.

    Article  CAS  PubMed  Google Scholar 

  6. Rodriguez LV, Terris MK . Risks and complications of transrectal ultrasound guided prostate needle biopsy: a prospective study and review of the literature. J Urol 1998; 160: 2115–2120.

    Article  CAS  PubMed  Google Scholar 

  7. Collins GN, Lloyd SN, Hehir M, McKelvie GB . Multiple transrectal ultrasound-guided prostatic biopsies—true morbidity and patient acceptance. Br J Urol 1993; 71: 460–463.

    Article  CAS  PubMed  Google Scholar 

  8. Clements R, Aideyan OU, Griffiths GJ, Peeling WB . Side effects and patient acceptability of transrectal biopsy of the prostate. Clin Radiol 1993; 47: 125–126.

    Article  CAS  PubMed  Google Scholar 

  9. Irani J, Fournier F, Bon D, Gremmo E, Dore B, Aubert J . Patient tolerance of transrectal ultrasound-guided biopsy of the prostate. Br J Urol 1997; 79: 608–610.

    Article  CAS  PubMed  Google Scholar 

  10. Paul R, Scholer S, van Randenborgh H, Kubler H, Alschibaja M, Busch R et al. Morbidity of prostatic biopsy for different biopsy strategies: is there a relation to core number and sampling region? Eur Urol 2004; 45: 450–455.

    Article  PubMed  Google Scholar 

  11. Naughton CK, Ornstein DK, Smith DS, Catalona WJ . Pain and morbidity of transrectal ultrasound guided prostate biopsy: a prospective randomized trial of 6 versus 12 cores. J Urol 2000; 163: 168–171.

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgements

We thank the members of Prostate Cancer Multicenter Study Group of the Korean Urological Oncologic Society: Dr Se Joong Kim, Dr Wun-Jae Kim, Dr Se Il Jung, Dr Kyung Seop Lee, Dr Jin Seon Cho, Dr Do Hwan Seong, Dr Jun Cheon, Dr Duck Ki Yoon, Dr Jaeil Chung, Dr Hyun Moo Lee and Dr Hong Bang Shim.

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  1. Division of Specific Organs Cancer, Urologic Oncology Clinic, National Cancer Center, Goyang, Republic of Korea

    K S Han & K H Lee

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  1. K S Han
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The Korean Urologic Oncology Society Prostate Cancer Study Group

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Correspondence to K H Lee.

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Han, K., Lee, K. & The Korean Urologic Oncology Society Prostate Cancer Study Group. Factors influencing pain during transrectal ultrasonography-guided prostate biopsy. Prostate Cancer Prostatic Dis 11, 139–142 (2008). https://doi.org/10.1038/sj.pcan.4501004

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