Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Cancer

Mixing cocktails

A major hurdle in treating cancer is that tumour cells acquire drug resistance. To overcome this problem, one strategy might be to fine-tune the right mixture of drugs that target specific molecules.

Your institute does not have access to this article

Relevant articles

Open Access articles citing this article.

Access options

Buy article

Get time limited or full article access on ReadCube.

$32.00

All prices are NET prices.

Figure 1: The battle of tumours and drugs.

References

  1. Sawyers, C. L. Genes Dev. 17, 2998–3010 (2003).

    CAS  Article  Google Scholar 

  2. Engelman, J. A. et al. Science 316, 1039–1043 (2007).

    ADS  CAS  Article  Google Scholar 

  3. Stommel, J. M. et al. Science 318, 287–290 (2007).

    ADS  CAS  Article  Google Scholar 

  4. Pao, W. et al. PLoS Med. 2, e73 (2005).

    Article  Google Scholar 

  5. Michor, F. et al. Nature 435, 1267–1270 (2005).

    ADS  CAS  Article  Google Scholar 

  6. Skaggs, B. J. et al. Proc. Natl Acad. Sci. USA 103, 19466–19471 (2006).

    ADS  CAS  Article  Google Scholar 

  7. Shah, N. P. et al. Cancer Cell 2, 117–125 (2002).

    CAS  Article  Google Scholar 

  8. Shah, N. P. et al. J. Clin. Invest. 117, 2562–2569 (2007).

    CAS  Article  Google Scholar 

  9. Talpaz, M. et al. N. Engl. J. Med. 354, 2531–2541 (2006).

    CAS  Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Sawyers, C. Mixing cocktails. Nature 449, 993–995 (2007). https://doi.org/10.1038/449993a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/449993a

Further reading

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing