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Ageing

From stem to stern

Immortality is the stuff of myth and legend, but lifespan extension is the subject of serious scientific inquiry. Exploring the causes and effects of ageing in stem cells should aid this quest.

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Figure 1: Interplay between factors and networks influencing ageing.

References

  1. Rando, T. A. Nature 441, 1080–1086 (2006).

    Article  CAS  ADS  Google Scholar 

  2. Nijnik, A. et al. Nature 447, 686–690 (2007).

    Article  CAS  ADS  Google Scholar 

  3. Rossi, D. J. et al. Nature 447, 725–729 (2007).

    Article  CAS  ADS  Google Scholar 

  4. Chambers, S. M. et al. PLoS Biol. 5, e201 (2007).

    Article  Google Scholar 

  5. Brack, A. S. et al. Science 317, 807–810 (2007).

    Article  CAS  ADS  Google Scholar 

  6. Finkel, T. & Holbrook, N. J. Nature 408, 239–247 (2000).

    Article  CAS  ADS  Google Scholar 

  7. Lombard, D. B. et al. Cell 120, 497–512 (2005).

    Article  CAS  Google Scholar 

  8. Shizuru, J. A., Negrin, R. S. & Weissman, I. L. Annu. Rev. Med. 56, 509–538 (2005).

    Article  CAS  Google Scholar 

  9. Dumble, M. et al. Blood 109, 1736–1742 (2007).

    Article  CAS  Google Scholar 

  10. Janzen, V. et al. Nature 443, 421–426 (2006).

    Article  CAS  ADS  Google Scholar 

  11. Tothova, Z. et al. Cell 128, 325–339 (2007).

    Article  CAS  Google Scholar 

Download references

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Brunet, A., Rando, T. From stem to stern. Nature 449, 288–291 (2007). https://doi.org/10.1038/449288a

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