Skip to main content

Thank you for visiting You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Genomic biology

The epigenomic era opens

Readout of information from the genome depends on intricate regulation of how DNA is packaged by proteins. The great endeavour to reveal how this packaging operates pan-genomically is now under way.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Rent or buy this article

Get just this article for as long as you need it


Prices may be subject to local taxes which are calculated during checkout

Figure 1: Genomic architecture, and eras of investigation.


  1. Mikkelsen, T. S. et al. Nature 448, 553–560 (2007).

    Article  ADS  CAS  Google Scholar 

  2. Barski, A. et al. Cell 129, 823–837 (2007).

    Article  CAS  Google Scholar 

  3. Watson, J. D. & Crick, F. H. C. Nature 171, 737–738 (1953).

    Article  ADS  CAS  Google Scholar 

  4. Lander, E. S. et al. Nature 409, 860–921 (2001).

    Article  ADS  CAS  Google Scholar 

  5. Venter, J. C. et al. Science 291, 1304–1351 (2001).

    Article  ADS  CAS  Google Scholar 

  6. Li, B., Carey, M. & Workman, J. L. Cell 128, 707–719 (2007).

    Article  CAS  Google Scholar 

  7. Jenuwein, T. & Allis, C. D. Science 293, 1074–1080 (2001).

    Article  CAS  Google Scholar 

  8. Bernstein, B. E., Meissner, A. & Lander, E. S. Cell 128, 669–681 (2007).

    Article  CAS  Google Scholar 

  9. Kapranov, P. et al. Science 316, 1484–1488 (2007).

    Article  ADS  CAS  Google Scholar 

  10. Albiez, H. et al. Chromosome Res. 14, 707–733 (2006).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations


Rights and permissions

Reprints and Permissions

About this article

Cite this article

Baylin, S., Schuebel, K. The epigenomic era opens. Nature 448, 548–549 (2007).

Download citation

  • Published:

  • Issue Date:

  • DOI:

This article is cited by


Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing