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Cancer

Broken genes in solid tumours

Mutations that cause portions of two genes to fuse together and form a hybrid gene are frequent in blood-related cancers. New findings implicate one such fusion gene in the most common type of lung cancer.

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Figure 1: The EML4–ALK fusion protein and lung cancer.

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Meyerson, M. Broken genes in solid tumours. Nature 448, 545–546 (2007). https://doi.org/10.1038/448545a

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