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An awakening

Neuroscientists and engineers are developing ways to help patients overcome paralysis and stroke. But what about mental function itself? Can medical intervention restore consciousness?

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  1. Sartre, J.-P. Existentialism and Human Emotions (Carol, New York, 1984).

    Google Scholar 

  2. Crick, F. & Koch, C. Nature Neurosci. 6, 119–126 (2003).

    Article  CAS  Google Scholar 

  3. Block, N. Trends Cogn. Sci. 9, 46–52 (2005).

    Article  Google Scholar 

  4. Schiff, N. D. et al. Nature 448, 600–603 (2007).

    Article  ADS  CAS  Google Scholar 

  5. Levy, D. E. et al. J. Am. Med. Assoc. 253, 1420–1426 (1985).

    Article  CAS  Google Scholar 

  6. Jones, E. G. Trends Neurosci. 24, 595–601 (2001).

    Article  CAS  Google Scholar 

  7. Shirvalkar, P., Seth, M., Schiff, N. D. & Herrera, D. G. Proc. Natl Acad. Sci. USA 103, 17007–17012 (2006).

    Article  ADS  CAS  Google Scholar 

  8. Merleau-Ponty, M. Phenomenology of Perception (Routledge & Kegan Paul, London, 1962).

    Google Scholar 

  9. Clark, A. Being There: Putting Brain, Body, and World Together Again (MIT Press, Cambridge, Massachusetts, 1997).

    Google Scholar 

  10. Cisek, P. Phil. Trans. R. Soc. B published online 11 Apr 2007 doi:10.1098/rstb.2007.2054 (2007).

  11. Gold, J. I. & Shadlen, M. N. Annu. Rev. Neurosci. 30, 535–574 (2007).

    Article  CAS  Google Scholar 

  12. Dosenbach, N. U. F. et al. Proc. Natl Acad. Sci. USA 104, 11073–11078 (2007).

    Article  ADS  CAS  Google Scholar 

  13. Fox, M. D. et al. Proc. Natl Acad. Sci. USA 102, 9673–9678 (2005).

    Article  ADS  CAS  Google Scholar 

  14. Kinney, H. C. & Samuels, M. A. J. Neuropathol. Exp. Neurol. 53, 548–558 (1994).

    Article  CAS  Google Scholar 

  15. Laureys, S., Owen, A. M. & Schiff, N. D. Lancet Neurol. 3, 537–546 (2004).

    Article  Google Scholar 

  16. Bernat, J. L. Neurology 58, 337–338 (2002).

    Article  Google Scholar 

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Shadlen, M., Kiani, R. An awakening. Nature 448, 539–540 (2007).

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