Figure 1: The role of Bicoid in dictating levels of gene expression during development. | Nature

Figure 1: The role of Bicoid in dictating levels of gene expression during development.

From: A ten per cent solution

Figure 1

a, A Drosophila embryo at the blastoderm stage of development stained with a fluorescently tagged antibody to Bicoid. b, The same embryo stained with a fluorescently tagged antibody to the Hunchback protein, the expression of which is determined by the Bicoid gradient. c, Gregor et al.4,5 found that the range of positions of threshold concentrations of Bicoid (xbcd) was twice that of the border of hunchback gene expression (xhb). The mean Bicoid pattern in a population (red solid line) is an average of the range of Bicoid levels in the population (dashed red lines). The mean expression profile of the hunchback gene (solid blue line) differs from its upper and lower limits of expression in the population (dashed blue lines) accordingly. (a and b are from ref. 10.)

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