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Cell biology

Caught in the traffic

Nature volume 448, pages 266–267 (2007)Cite this article

In mice, deletion of the Rab8 protein disrupts organized molecular distribution to membranes of intestinal epithelial cells. Death by starvation follows, exactly as it does in humans with microvillus inclusion disease.

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Figure 1: The many functions of Rab8.

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Authors and Affiliations

  1. Departments of Ophthalmology and Cell and Developmental Biology, Aparna Lakkaraju and Enrique Rodriguez-Boulan are at the Margaret M. Dyson Vision Research Institute, Weill Medical College of Cornell University, New York, New York 10021, USA. boulan@med.cornell.edu,

    Aparna Lakkaraju & Enrique Rodriguez-Boulan

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  1. Aparna Lakkaraju
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  2. Enrique Rodriguez-Boulan
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Lakkaraju, A., Rodriguez-Boulan, E. Caught in the traffic. Nature 448, 266–267 (2007). https://doi.org/10.1038/448266a

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