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Neurophysiology

Channelling cold reception

Perception of cold and hot is one of life's essentials. Three research teams find that, when a temperature-sensing receptor is deleted in mice, the animals lose their response to a range of cold temperatures.

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Figure 1: Sensing cold.

References

  1. Bernstein, J. Die fünf Sinne des Menschen (Brockhaus, Leipzig, 1875).

    Google Scholar 

  2. Voets, T., Talavera, K., Owsianik, G. & Nilius, B. Nature Chem. Biol. 1, 85–92 (2005).

    CAS  Article  Google Scholar 

  3. Dhaka, A., Viswanath, V. & Patapoutian, A. Annu. Rev. Neurosci. 29, 135–161 (2006).

    CAS  Article  Google Scholar 

  4. Colburn, R. W. et al. Neuron 54, 379–386 (2007).

    CAS  Article  Google Scholar 

  5. Dhaka, A. et al. Neuron 54, 371–378 (2007).

    CAS  Article  Google Scholar 

  6. Bautista, D. M. et al. Nature 448, 204–208 (2007).

    ADS  CAS  Google Scholar 

  7. McKemy, D. D., Neuhausser, W. M. & Julius, D. Nature 416, 52–58 (2002).

    ADS  CAS  Article  Google Scholar 

  8. Proudfoot, C. J. et al. Curr. Biol. 16, 1591–1605 (2006).

    CAS  Article  Google Scholar 

  9. Chung, M. K. & Caterina, M. J. Neuron 54, 345–347 (2007).

    CAS  Article  Google Scholar 

  10. Zimmermann, K. et al. Nature 447, 856–859 (2007).

    ADS  Article  Google Scholar 

  11. Hensel, H. & Zotterman, Y. J. Neurophysiol. 14, 377–385 (1951).

    CAS  Article  Google Scholar 

  12. Schmidt, R. F. & Thews, G. Physiologie des Menschen 214–217 (Springer, Heidelberg, 1990).

  13. Lee, H. & Caterina, M. J. Pflügers Arch. Eur. J. Physiol. 451, 160–167 (2005).

    CAS  Article  Google Scholar 

  14. Conti, B. et al. Science 314, 825–828 (2006).

    ADS  CAS  Article  Google Scholar 

Download references

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Nilius, B., Voets, T. Channelling cold reception. Nature 448, 147–148 (2007). https://doi.org/10.1038/448147a

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