Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Cell biology

Aneuploidy and cancer

Nature volume 446, pages 38–39 (2007)Cite this article

Aneuploidy is the condition in which a cell has extra or missing chromosomes, and is often associated with tumours. But whether it is a cause or a consequence of cancer remains a vexed question.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

  • Purchase on SpringerLink
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Different routes to aneuploidy.

References

  1. Sotillo, R. et al. Cancer Cell 11, 9–23 (2007).

    Article  CAS  Google Scholar 

  2. Weaver, B. A., Silk, A. D., Montagna, C., Verdier-Pinard, P. & Cleveland, D. W. Cancer Cell 11, 25–36 (2007).

    Article  CAS  Google Scholar 

  3. Kapoor, T. M. et al. Science 311, 388–391 (2006).

    Article  ADS  CAS  Google Scholar 

  4. Kops, G. J., Weaver, B. A. & Cleveland, D. W. Nature Rev. Cancer 5, 773–785 (2005).

    Article  CAS  Google Scholar 

  5. Baker, D. J., Chen, J. & van Deursen, J. M. Curr. Opin. Cell Biol. 17, 583–589 (2005).

    Article  CAS  Google Scholar 

  6. Abrieu, A., Kahana, J. A., Wood, K. W. & Cleveland, D. W. Cell 102, 817–826 (2000).

    Article  CAS  Google Scholar 

  7. Boveri, T. The Origin of Malignant Tumors (Williams & Wilkins, Baltimore, 1914).

    Google Scholar 

  8. Rajagopalan, H., Nowak, M. A., Vogelstein, B. & Lengauer, C. Nature Rev. Cancer 3, 695–701 (2003).

    Article  CAS  Google Scholar 

  9. Maser, R. S. & DePinho, R. A. Science 297, 565–569 (2002).

    Article  ADS  CAS  Google Scholar 

  10. Hernando, E. et al. Nature 430, 797–802 (2004).

    Article  ADS  CAS  Google Scholar 

  11. Fujiwara, T. et al. Nature 437, 1043–1047 (2005).

    Article  ADS  CAS  Google Scholar 

  12. Weaver, B. A., Silk, A. D. & Cleveland, D. W. Nature 442, E9–E10 (2006).

    Article  ADS  CAS  Google Scholar 

  13. Storchova, Z. et al. Nature 443, 541–547 (2006).

    Article  ADS  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. David Pellman is at the Dana-Farber Cancer Institute, Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA. david_pellman@dfci.harvard.edu,

    David Pellman

Authors
  1. David Pellman
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Pellman, D. Aneuploidy and cancer. Nature 446, 38–39 (2007). https://doi.org/10.1038/446038a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/446038a

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing