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Virology

Holed up in a natural crystal

Insect viruses that cause polyhedrosis produce infectious microcrystals within a cell. These inclusions were used in a study that pushed the state of the crystallographic art to explain their exceptional stability.

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Figure 1: Intracellular microcrystals.
Figure 2: Ribbon illustration of the polyhedrin trimer.

References

  1. Dodson, G. & Steiner, D. Curr. Opin. Struct. Biol. 8, 189–194 (1998).

    Article  CAS  Google Scholar 

  2. Giembycz, M. A. & Lindsay, M. A. Pharmacol. Rev. 51, 213–340 (1999).

    CAS  PubMed  Google Scholar 

  3. Rohrmann, G. F. J. Gen. Virol. 67, 1499–1513 (1986).

    Article  CAS  Google Scholar 

  4. Coulibaly, F. et al. Nature 446, 97–101 (2007).

    Article  ADS  CAS  Google Scholar 

  5. Fujiwara, T. et al. Appl. Entomol. Zool. 19, 402–403 (1984).

    Article  Google Scholar 

  6. Anduleit, K. et al. Protein Sci. 14, 2741–2743 (2005).

    Article  CAS  Google Scholar 

  7. Hill, C. L. et al. Nature Struct. Biol. 6, 565–568 (1999).

    Article  CAS  Google Scholar 

  8. Di, X., Sun, Y. K., McCrae, M. A. & Rossmann, M. G. Virology 180, 153–158 (1991).

    Article  CAS  Google Scholar 

  9. http://sls.web.psi.ch/view.php/beamlines/px/index.html

  10. Riekel, C., Burghammer, M. & Schertler, G. Curr. Opin. Struct. Biol. 15, 556–562 (2005).

    Article  CAS  Google Scholar 

  11. Lawrence, M. C. & Colman, P. M. J. Mol. Biol. 234, 946–950 (1993).

    Article  CAS  Google Scholar 

  12. Kantardjieff, K. A. & Rupp, B. Protein Sci. 12, 1865–1871 (2003).

    Article  CAS  Google Scholar 

  13. Ikeda, K. et al. J. Virol. 75, 988–995 (2001).

    Article  CAS  Google Scholar 

  14. Ikeda, K. et al. Proteomics 6, 54–66 (2006).

    Article  CAS  Google Scholar 

  15. http://www.pymol.org

Download references

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Rey, F. Holed up in a natural crystal. Nature 446, 35–36 (2007). https://doi.org/10.1038/446035a

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